Comparison of saliva and serum for HIV surveillance in developing countries
作者： R.R. Frerichs , M.T. Htoon , N. Eskes , S. Lwin
DOI: 10.1016/0140-6736(92)92755-5
关键词: Human immunodeficiency virus (HIV) 、 Vial 、 Antibody 、 Immunology 、 Viral disease 、 Hiv surveillance 、 Saliva 、 Acquired immunodeficiency syndrome (AIDS) 、 Gold standard (test) 、 Internal medicine 、 Medicine
摘要: Abstract Saliva has been proposed as a non-invasive alternative to serum for HIV antibody testing. In field study in Myanmar (formerly Burma), we evaluated such an identify the frequency of infection surveillance programme high-risk and low-risk sentinel groups. Duplicate vials saliva were collected from 479 1039 subjects. One vial each pair was analysed blind two laboratories, one USA other Myanmar. The US laboratory followed WHO confirmatory strategy III with three different enzymelinked immunosorbent assays (ELISAs), while I ELISA. Serum testing gold standard. Cambridge ELISA more effective tool (sensitivity 90·5%, specificity 99·5-100%) describing subjects antibodies than supplied by (95·9% 98·3%, respectively). is recommended safe programmes developing countries.
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