作者: Francisco Mesa , Antonio Magán-Fernández , Dragana Nikolic , Rafael Marfil-Alvarez , Luigi Nibali
DOI: 10.2217/CLP.14.8
关键词: Chronic periodontitis 、 Periodontitis 、 Lipoprotein 、 Blood lipids 、 Endocrinology 、 Dental plaque 、 Immunology 、 Type 2 Diabetes Mellitus 、 Porphyromonas gingivalis 、 Low-density lipoprotein 、 Medicine 、 Internal medicine
摘要: Periodontitis, one of the most common chronic infections in adults, is characterized by accumulation dental plaque and infection Gram-negative pathogenic bacteria, which further lead to destruction periodontal tissues. A relationship between periodontitis abnormalities lipid and/or lipoprotein metabolism not well understood yet. Periodontitis associated with elevated proatherogenic plasma lipids, including small dense LDL, while oxidized LDL may act as an inflammatory stimulant periodontitis. Periodontal pathogens directly modify lipoprotein, protective characteristics HDL, contribute development metabolic syndrome, Type 2 diabetes mellitus coronary atherosclerosis. On other hand, treatment modest HDL-C increases, LDL-C decreases consequently lower cardiometabolic risk. Thus, oral check-ups improved hygiene reduce risk antibodies against pathogens. Identific...