Papillomaviruses: General Features

作者: H.U. Bernard

DOI: 10.1016/B978-012374410-4.00688-9

关键词: CapsidGenital wartsGenomeVirusVaccinationViral envelopeVirologyBiologyCommon wartsGeneImmunology

摘要: Papillomaviruses are nonenveloped viruses with an 8 kbp double-stranded, circular DNA genome, which encodes six early and two late genes. The products of the genes regulate transcription replication virus mitosis infected cell. form viral capsid important for infection process. infect mucosal cutaneous epithelia in humans other mammals. There many types remotely related papillomaviruses, some great interest public health, as they cause, a type-specific manner, cervical anogenital cancers, genital laryngeal warts, skin warts. Treatment papillomavirus lesions is done mostly by surgical procedures. Recently introduced prophylatic vaccinations may reduce incidence most future.

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