Central hemodynamics of hypertensive disorders in pregnancy.

摘要: Background Preeclampsia is characterized by an increase in peripheral vasoconstriction. Studies of central hemodynamics are limited. Noninvasive evaluation aortic stiffness and pressure waveform possible applanation tonometry. We determined pulse wave velocity (PWV), augmentation index (AI), subendocardial viability ratio (SEVR), the to brachial amplification normotensive, hypertensive, preeclamptic pregnancies. Methods In 51 38 33 pregnancies we measured carotid-femoral PWV. The AI, SEVR, pressures were analysis derived from radial artery. Measurements performed lateral position after 10 min rest. Linear regression models ANOVA multiple comparisons used for statistical analyses. Results There no differences age or other baseline characteristics. mean PWV groups was 5.1 m/sec (SD 0.6), 6.2 1.0), 7.0 1.3), respectively. AI 6.7% 14.0), 17.7% 15.9), 31.1% 12.4), SEVR 1.38 0.2), 1.50 (0.2), 1.48 (0.3), Central 1.6 1.4 1.3 After adjustment blood pressure, significant remained between groups. Conclusions hypertensive pregnancies, significantly higher as compared normotensive pregnancy. Amplification lower resulting relatively pressure. Nevertheless, supply demand heart not impaired