Tissue phospholipid fatty acid composition in the diabetic rat

作者: Y. S. Huang , D. F. Horrobin , M. S. Manku , J. Mitchell , M. A. Ryan

DOI: 10.1007/BF02534790

关键词: Fatty acidArachidonic acidBiochemistryInternal medicineAdrenal glandKidneyDiabetes mellitusLinoleic acidPhospholipidClinical chemistryBiologyEndocrinologyOrganic chemistryCell biology

摘要: Tissue phospholipid fatty acid compositions in streptozotocin-induced diabetic rats were studied. The major changes liver, plasma, erythrocyte and heart increased proportions of linoleic dihomo-γ-linolenic acids a decreased proportion aracchidonic acid. latter was not significantly changed phospholipids kidney, adrenal gland testis. Skin showed an increase the arachidonic reduction desaturating activity diabetes may be regulated differently different tissues.

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