Atrial natriuretic factor: a new hormone of cardiac origin.

摘要: Publisher Summary This chapter presents atrial natriuretic factor (ANF). Although there are several major issues that await resolution, a general concept of the possible role this new hormone is beginning to take shape. The information available at present does not permit any definitive conclusions about ANF in physiological or pathological processes. actions infused ANF, together with its distribution central nervous system, suggest fundamental interaction hormonal and neural control fluid electrolyte balance arterial pressure circulation. In addition direct indirect effects on renal excretory function, circumstantial evidence might regulate vascular volume by increasing capillary permeability. There also increased levels plasma can be sustained chronically pathologic states, such as congestive heart failure, characterized marked overload chronic increases wall tension, however, little indication involved long-term regulation extracellular volume, function under normal conditions. has been considerable excitement over potential therapeutic agent, it will necessary first have clearer understanding endogenous health disease.