Kiwifruit and Cancer: An Overview of Biological Evidence

作者: Giuseppe Lippi , Camilla Mattiuzzi

DOI: 10.1080/01635581.2019.1650190

关键词: Internal medicineActinidia chinensisBiological evidenceCancerMedicineMalignancyOncologyActinidia deliciosaMEDLINEActinidiaColorectal cancer

摘要: Kiwifruit consumption is associated with many favorable health benefits. This article hence aimed to provide an overview on potential effects of kiwifruit cancer development or progression. An electronic search was performed in Medline and Web Science, for identifying original studies exploring the relationship between progression, both vivo vitro. The following keywords were used: "Kiwifruit" OR "Kiwi" "Actinidia deliciosa" chinensis," combination "cancer" "malignancy" "neoplasm." Overall, 58 items could be retrieved, fifty which excluded since they did not fulfilled all our criteria. Eight (five vitro studies, two human intervention trials, one study) finally included this critical literature review. Taken together, results these published suggest that supplementation may direct indirect anticancer effects, former likely due ascorbic acid-mediated reduction DNA oxidative injury cytotoxic effect cell lines, latter more attributable enhanced daily bowel movements increased intestinal fecal content lactic acid bacteria, would contribute lower risk malignancies, especially colorectal cancer.

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