A radioimmunoassay of primary bile acid conjugates in human serum.

作者: Luigi Barbara , Davide Festi , Giuseppe Mazzella , Rita Aldini , Enrico Roda

DOI: 10.1007/BF02879481

关键词: Liver diseasePrimary biliary cirrhosisRadioimmunoassayBile acidLiver function testsChenodeoxycholic acidEndocrinologyQuantitative analysis (chemistry)Cholic acidInternal medicineChemistry

摘要: The fasting levels of chenodeoxycholic and cholic acid conjugates in various groups patients [25 healthy subjects, 20 with chronic active liver disease (CALD), 21 primary biliary cirrhosis (PBC) 5 cholesterol gallstones before after therapy] were determined by using a sensitive, accurate precise radioimmunoassay. results obtained this method compared those gas-chromatographic methylation acetylation the bile acids 2 m x 0.4 cm glass column packed 3% AN 600 on Anakrom Q 110-120 mesh. both methods are agreement; therefore used can be applied for quantitative analysis. In diagnosis, measurement serum levels, or meals, proved to very sensitive method, although further correlations necessary standard function tests.

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