Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
作者： Zachary T. Schafer , Alexandra R. Grassian , Loling Song , Zhenyang Jiang , Zachary Gerhart-Hines
DOI: 10.1038/NATURE08268
关键词: Anoikis 、 Signal transduction 、 Cell culture 、 Extracellular matrix 、 Glucose uptake 、 Cell biology 、 Kinase 、 Apoptosis 、 Chemistry 、 Glucose transporter 、 Multidisciplinary
摘要: … This rescue was found to be dependent on stimulation of fatty acid oxidation, which is inhibited by detachment-induced reactive oxygen species (ROS). The significance of these …
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