Successful Treatment of Chronic Stromal Acanthamoeba Keratitis with Oral Voriconazole Monotherapy

作者: Elmer Y Tu , Charlotte E Joslin , Megan E Shoff

DOI: 10.1097/ICO.0B013E3181CBFA2C

关键词: DermatologyMedicineStromal cellTraditional therapyImmunologyAcanthamoebaAcanthamoeba keratitisKeratitisCorneaPharmacotherapyVoriconazole

摘要: Purpose:To describe the treatment of chronic stromal Acanthamoeba keratitis (AK) with oral voriconazole monotherapy.Methods:All cases AK recalcitrant to traditional therapy subsequently treated systemic seen at University Illinois Eye and Ear Infirmary bet

参考文章(15)
Yasuhisa Ishibashi, Yujiro Matsumoto, Takamichi Kabata, Ryoko Watanabe, Sachiko Hommura, Kazuo Yasuraoka, Keiich Ishii, Oral Itraconazole and Topical Miconazole With Debridement for Acanthamoeba Keratitis American Journal of Ophthalmology. ,vol. 109, pp. 121- 126 ,(1990) , 10.1016/S0002-9394(14)75974-4
FREDERICK L. SCHUSTER, B. JOSEPH GUGLIELMO, GOVINDA S. VISVESVARA, In-vitro activity of miltefosine and voriconazole on clinical isolates of free-living amebas: Balamuthia mandrillaris, Acanthamoeba spp., and Naegleria fowleri. Journal of Eukaryotic Microbiology. ,vol. 53, pp. 121- 126 ,(2006) , 10.1111/J.1550-7408.2005.00082.X
Natasha Lim, David Goh, Catey Bunce, Wen Xing, Graham Fraenkel, Tom R.G. Poole, Linda Ficker, Comparison of Polyhexamethylene Biguanide and Chlorhexidine as Monotherapy Agents in the Treatment of Acanthamoeba Keratitis American Journal of Ophthalmology. ,vol. 145, pp. 130- 135 ,(2008) , 10.1016/J.AJO.2007.08.040
William Mathers, Use of Higher Medication Concentrations in the Treatment of Acanthamoeba Keratitis Archives of Ophthalmology. ,vol. 124, pp. 923- 923 ,(2006) , 10.1001/ARCHOPHT.124.6.923
Lawrence W. Hirst, W. Richard Green, William Merz, Cindy Kaufmann, G.S. Visvesvara, Allan Jensen, Malin Howard, Management of Acanthamoeba Keratitis Ophthalmology. ,vol. 91, pp. 1105- 1111 ,(1984) , 10.1016/S0161-6420(84)34200-2
Patrick Gooi, Matthew Lee-Wing, Seymour Brownstein, Sherif El-Defrawy, W Bruce Jackson, George Mintsioulis, Acanthamoeba keratitis: persistent organisms without inflammation after 1 year of topical chlorhexidine. Cornea. ,vol. 27, pp. 246- 248 ,(2008) , 10.1097/ICO.0B013E31815B82A2
M.B. Moore, J.P. McCulley, M. Luckenbach, H. Gelender, C. Newton, M.B. McDonald, G.S. Visvesvara, Acanthamoeba keratitis associated with soft contact lenses. American Journal of Ophthalmology. ,vol. 100, pp. 396- 403 ,(1985) , 10.1016/0002-9394(85)90500-8
R. Walia, J.G. Montoya, G.S. Visvesvera, G.C. Booton, R.L. Doyle, A case of successful treatment of cutaneous Acanthamoeba infection in a lung transplant recipient Transplant Infectious Disease. ,vol. 9, pp. 51- 54 ,(2007) , 10.1111/J.1399-3062.2006.00159.X
YF Yang, M Matheson, JKG Dart, IA Cree, None, Persistence of acanthamoeba antigen following acanthamoeba keratitis British Journal of Ophthalmology. ,vol. 85, pp. 277- 280 ,(2001) , 10.1136/BJO.85.3.277