Management of Acanthamoeba Keratitis

摘要: A recalcitrant corneal ulcer resulted in an extensive opacity requiring penetrating keratoplasty. Histopathologic studies and subsequent cultures established the diagnosis of Acanthamoeba keratitis. second transplant was performed due to a culture-proven recurrence keratitis both recipient graft, with progressive thinning. This has remained clear for six months on systemic ketoconazole topical miconazole drops. case demonstrates difficulty initial apparent successful medical control infection despite transplantation into infected bed.