High uptake of hepatitis C virus treatment in HIV/hepatitis C virus co-infected patients attending an integrated HIV/hepatitis C virus clinic.

摘要: Hepatitis C virus (HCV) is a major cause of liver disease in HIV-infected patients. The HCV treatment outcomes and barriers to referral were examined centre with HIV/HCV co-infection clinic. Patients who antibody positive for both HIV between 1987 January 2009 identified. A retrospective chart review was undertaken. Multivariate analysis performed assess predictors clinic referral. Data collected on 386 patients; 202/386 had been referred the 107/202 treatment. In addition, 29/202 undergoing pretreatment work-up. Overall sustained virologic response (SVR) 44%; SVR equivalent those acquired infection from intravenous drug use (IDU) others. On multivariate analysis, patients missed appointments, younger, active IDU advanced not offered less likely be Patients attending more have screened hepatocellular carcinoma than general service. Two-thirds engaged programme. Dedicated clinics lower threshold improve management co-infected