Transcriptional control: SWItched-on mobility

作者: Dmitry Guschin , Alan P. Wolffe

DOI: 10.1016/S0960-9822(99)80473-4

关键词: Transcription factorTranscription (biology)HistoneChromatinBiologyGeneticsCell biologyProtein subunitDNA-binding proteinTranscriptional regulationNucleosome

摘要: Recent studies have shown that two nucleosome-remodeling complexes, NURF and CHRAC, open chromatin for transcription replication by using their common catalytic subunit, the nucleosomal ATPase ISWI, to increase mobility of nucleosomes relative DNA sequence.

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