Transcriptional repression by neuron-restrictive silencer factor is mediated via the Sin3-histone deacetylase complex.
作者： Avtar Roopra , Lisa Sharling , Ian C. Wood , Teresa Briggs , Ulla Bachfischer
DOI: 10.1128/MCB.20.6.2147-2157.2000
关键词: Transcription factor 、 SIN3A 、 Molecular biology 、 Regulation of gene expression 、 Promoter 、 Biology 、 Repressor 、 Transcriptional regulation 、 RE1-silencing transcription factor 、 Histone deacetylase activity
摘要: … This repression has a genetic requirement for the yeast SIN3 … SIN3/HDAC complex is important for REST/NRSF-mediated silencing and provide evidence that this corepressor complex …
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