Prognostic factors of non-ampullary duodenal adenocarcinoma.

作者: Teijiro Hirashita , Masayuki Ohta , Kazuhiro Tada , Kunihiro Saga , Hiroomi Takayama

DOI: 10.1093/JJCO/HYY086

关键词: MedicineInternal medicineLymph nodeGastroenterologyRare diseaseAmpulla of VaterStage (cooking)Chemotherapy regimenColorectal cancerCarcinomaDuodenal adenocarcinoma

摘要: Background Non-ampullary duodenal adenocarcinoma, excluding carcinoma in the ampulla of Vater, is a rare disease. Although several prognostic factors have been reported, they remain controversial due to rarity non-ampullary adenocarcinoma. The aims this study were investigate patients with adenocarcinoma and assess chemotherapy recurrence. Patients methods Records 25 who underwent surgical treatment for from 2004 2016 retrospectively reviewed. relationship between clinicopathological outcomes was investigated. Results Serum level CA19-9, gross appearance, tumor size, invasion, lymph node metastases, TNM stage lymphatic vascular invasion significant risk recurrence received according regimens used treat colorectal cancer had better prognosis than those without (P = 0.016). Conclusion Advanced has poor prognosis, but possibly improves recurrent

参考文章(27)
Thuy B. Tran, Motaz Qadan, Monica M. Dua, Jeffrey A. Norton, George A. Poultsides, Brendan C. Visser, Prognostic relevance of lymph node ratio and total lymph node count for small bowel adenocarcinoma Surgery. ,vol. 158, pp. 486- 493 ,(2015) , 10.1016/J.SURG.2015.03.048
Bouthaina S. Dabaja, Dima Suki, Barbara Pro, Mark Bonnen, Jaffer Ajani, Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients Cancer. ,vol. 101, pp. 518- 526 ,(2004) , 10.1002/CNCR.20404
Fu-Chih Hung, Chung-Mou Kuo, Seng-Kee Chuah, Chung-Huang Kuo, Yaw-Sen Chen, Sheng-Nan Lu, Chi-Sin Chang Chien, Clinical analysis of primary duodenal adenocarcinoma: an 11-year experience. Journal of Gastroenterology and Hepatology. ,vol. 22, pp. 724- 728 ,(2007) , 10.1111/J.1440-1746.2007.04935.X
Nova M. Ryder, Primary Duodenal Adenocarcinoma Archives of Surgery. ,vol. 135, pp. 1070- 1074 ,(2000) , 10.1001/ARCHSURG.135.9.1070
J.C. Haan, T.E. Buffart, P.P. Eijk, M.A. van de Wiel, W.N. van Wieringen, P.D. Howdle, C.J.J. Mulder, C.J. van de Velde, P. Quirke, I.D. Nagtegaal, N.C.T. van Grieken, H. Grabsch, G.A. Meijer, B. Ylstra, Small bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers Annals of Oncology. ,vol. 23, pp. 367- 374 ,(2012) , 10.1093/ANNONC/MDR122
Hyung Geun Lee, Dong Do You, Kwang Yeol Paik, Jin Seok Heo, Seong Ho Choi, Dong Wook Choi, Prognostic Factors for Primary Duodenal Adenocarcinoma World Journal of Surgery. ,vol. 32, pp. 2246- 2252 ,(2008) , 10.1007/S00268-008-9678-6
Ian A. Spira, Ali Ghazi, William I. Wolff, Primary adenocarcinoma of the duodenum Cancer. ,vol. 39, pp. 1721- 1726 ,(1977) , 10.1002/1097-0142(197704)39:4<1721::AID-CNCR2820390450>3.0.CO;2-M
Jason S. Gold, Laura H. Tang, Mithat Gönen, Daniel G. Coit, Murray F. Brennan, Peter J. Allen, Utility of a Prognostic Nomogram Designed for Gastric Cancer in Predicting Outcome of Patients with R0 Resected Duodenal Adenocarcinoma Annals of Surgical Oncology. ,vol. 14, pp. 3159- 3167 ,(2007) , 10.1245/S10434-007-9542-1
T. Buchbjerg, C. Fristrup, M.B. Mortensen, The incidence and prognosis of true duodenal carcinomas. Surgical Oncology-oxford. ,vol. 24, pp. 110- 116 ,(2015) , 10.1016/J.SURONC.2015.04.004