A radical cyclisation strategy to α-spiro-β-methylene-γ-butyrolactones. Total synthesis of (±)-norbakkenolide-A
作者： Adusumilli Srikrishna , Sankuratri Nagaraju , G. Veera Raghava Sharma
DOI: 10.1039/C39930000285
关键词: Chemistry 、 Methylene 、 Organic chemistry 、 Sesquiterpene 、 Hemiacetal 、 Steroid 、 Enol 、 Lactone 、 Total synthesis 、 Reagent
摘要: The 5-exo-dig radical cyclisation reaction of the bromoacetals 9, obtained from enol ethers 8, and treatment resulting hemiacetal 10 with Jones′ reagent transforms cyclic ketones 7 12 into α-spiro-β-methylene-γ-butyrolactones 11 norbakkenolide-A 2.
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