Usefulness of quantitative baseline ST-segment elevation for predicting outcomes after primary coronary angioplasty or fibrinolysis (results from the DANAMI-2 trial)

作者: Maria Sejersten , Rasmus S Ripa , Charles Maynard , Galen S Wagner , Henning Rud Andersen

DOI: 10.1016/J.AMJCARD.2005.09.099

关键词: StrokeCardiologyFibrinolysisElectrocardiographyST elevationQuartileMedicineMultivariate analysisInternal medicineAngioplastyST segment

摘要: The DANAMI-2 trial showed a 40% decrease in the composite end point with primary coronary angioplasty versus fibrinolysis. This result was primarily driven by reinfarction, no significant difference mortality or stroke rates. objective of this study to determine prognostic value sum ST-segment elevation (∑ST↑) on baseline electrocardiography patients who were randomized receive In DANAMI-2, 1,450 had deviation measurements and assigned quartiles according ∑ST↑: 0 6.5, 7.0 9.5, 10.0 14.5, 15.0 70.5 mm. component end-point rates at 30 days determined for each quartile chi-square trend statistic used compare across ∑ST↑. occurred more often increasing ∑ST↑ (p = 0.05). With regard points, only increased significantly 0.03), whereas reinfarction did not. By multivariate analysis, age independent predictors mortality. relative benefit similar all quartiles. conclusion, magnitude correlates days, thus driving rate. Regardless ∑ST↑, lower rate than

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