Effect of intravenous streptokinase on the relation between initial ST-predicted size and final QRS-estimated size of acute myocardial infarcts.

摘要: Thrombolytic therapy has been documented to reduce acute myocardial infarct size. The previously established relation between initial ST segment elevation and final electrocardiographic (ECG) size in patients without coronary reperfusion might therefore be altered by thrombolytic therapy. effect of intravenous streptokinase on this was studied 73 with infarction who had participated the Second International Study Infarct Survival (ISIS-2). Patients received were considered as one group did not receive a control group. Final size, which estimated from QRS score, predicted admission standard ECG developed formulas based elevation. In 40 there no change ST-predicted QRS-estimated (median 17.7% versus 18.3%; p = NS). 33 group, highly significant decrease 21.9% 16.2%; less than 0.0002). This found for both anterior 23.7% 19.5%; 0.03) inferior 12.0%; 0.001) locations. Multiple regression analysis adjusting differences confirmed significance difference (p 0.006). Based variability percent threshold greater or equal 20% is required identification salvage.(ABSTRACT TRUNCATED AT 250 WORDS)