作者: Erin Lavik , Horst von Recum
DOI: 10.1021/NN201371A
关键词: Nanomedicine 、 Nanomaterials 、 Nanotechnology 、 Computer science 、 Risk analysis (engineering) 、 Translational medicine
摘要: There are a range of definitions for nanomaterials and length scales that considered nano, but one thing is consistent among fields: small special. Nanomaterials have the potential to tremendous impact on medical treatments. In example, permitting tracking cells via magnetic resonance imaging (MRI) in clinical trials assess efficacy safety cellular therapies. second acting as drug-delivery vehicles targeted delivery therapies increase reduce side effects. However, there distinct challenges must be development application these materials, including careful analysis distribution clearance their off-target By carefully assessing materials early at bench, may able move successful approaches through clinic more rapidly, which indeed goal field. For far too many conditions diseases, tools we less than adequate, fill void. To realize this potential, investigators willing invest time resources develop translate technologies point where risk low enough they real, commercial possibilities. Working collaboratively leveraging experience play important roles moving preclinical testing. It requires incredible dedication teams researchers, result new treatments