Ovarian consequences of the transient interruption of combined oral contraceptives.

摘要: The combined oral contraceptive pill is an efficient means of contraception. It acts at different levels the genital tract. Despite its efficiency, it universally suggested that patients take regular daily intervals. Little attention has been given to question what happens if you miss one day or more. A study was undertaken evaluate consequences misses times cycle. Forty-seven young, healthy, normally menstruating voluntarily enrolled. All were Cilest (ethinyl estradiol 35 micrograms and norgestimate 250 mg, Cilag France) for 21 days without any misses. Then, after a 7-day interval, they prescribed (group 1), two 2), three 3) four misses, occur respectively on 1 a), 6 b), 12 c) 18 d) new cycle; supplementary recommended. Four had no served as controls. Ovarian function evaluated with estrogen measurements (E1 + E2 enzymatic dosage, BioMerieux, ultrasound examinations. When required, because significant increase in follicular growth detected ultrasound, LH progesterone measured. None experienced normal ovulation. (1 control, from group 2a, 2 3a) image ultrasounds. One them rupture, but none surge progesterone.(ABSTRACT TRUNCATED AT WORDS)