Pregnancy in women with idiopathic thrombocytopaenic purpura.

摘要: Introduction: Idiopathic thrombocytopaenic purpura (ITP) is a common haematological disorder in young women. The management of ITP pregnancy controversial, particularly with regards to the mode delivery. To date,there no systematic study outcome these pregnancies Singapore. Aim: outcomes Asian women proven diagnosis ITP. Materials and Methods: Retrospective of27 18 managed at Singapore General Hospital from 1 January 1994 30 June 2001. Results: mean age was years (range, 20 41 years) parity 0 3). Thrombocytopaenia (platelet count <150 x 10 9 /L) occurred (67%). There were 3 first trimester missed abortions (11%), termination (4%), stillbirth (4%) 22 livebirths (81%) this series. delivery spontaneous vaginal 14 (64%), vacuum extraction 2 (9%), elective caesarean section 5 (23%) emergency woman (4%). All liveborn neonates delivered good condition term. Neonatal thrombocytopaenia 4 (18%). Two had cord platelet counts less than 50 /L required therapy corticosteroids intravenous immune globulins. No bleeding complications any neonates. Conclusion: Our experience supports increasingly prevalent practice managing conservative approach investigations treatment. Caesarean sections should be performed for obstetric indications only, given rarity offspring lack evidence support its role prevention neonatal intracranial haemorrhage.