Neutrophil chemotaxis in refractory cases of periodontitis.

作者: Herbert I. Oshrain , Bernard Telsey , Irwin D. Mandel

DOI: 10.1111/J.1600-051X.1987.TB01514.X

关键词: ChemotaxisPolymorphonuclear NeutrophilsPeriodontitisNeutrophil chemotaxisGingival and periodontal pocketRefractoryPathologyIn vivoCellMedicine

摘要: Abstract Refractory cases of periodontitis were assayed for chemotaxis polymorphonuclear neutrophilic leukocytes using an in vivo assay. 9 refractory patients and normal studied. When cell counts plotted against time, showed a single peak at 25–30 min after casein (chemo-attractant) challenge, whereas 2 3 peaks PMN's varying time intervals. 5 the this pattern tests sulci as well deep periodontal pockets. 4 double This suggests that some have intrinsic chemotactic defect neutrophils while others may be secondary phenomenon. It appears with characteristic response was reported LJP.

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