Recent advances in the synthesis of benzimidazoles (microreview)

作者： Mantas Jonušis , Inga Čikotienė

关键词: Benzimidazole 、 Chemistry 、 Combinatorial chemistry 、 Organic chemistry

摘要: This microreview focuses on the most recent literature (past 3 years) covering new approaches for substituted benzimidazole synthesis.

参考文章(16)

Yanjun Xie, Jun Wu, Xingzong Che, Ya Chen, Huawen Huang, Guo-Jun Deng, Efficient pyrido[1,2-a]benzimidazole formation from 2-aminopyridines and cyclohexanones under metal-free conditions Green Chemistry. ,vol. 18, pp. 667- 671 ,(2016) , 10.1039/C5GC01978H

Masayoshi Arai, Chisu Han, Yoshi Yamano, Andi Setiawan, Motomasa Kobayashi, Aaptamines, marine spongean alkaloids, as anti-dormant mycobacterial substances. Journal of Natural Medicines. ,vol. 68, pp. 372- 376 ,(2014) , 10.1007/S11418-013-0811-Y

A. Selen Gurkan-Alp, Hakan Göker, Mehmet Alp, Tulin Ozkan, Asuman Sunguroglu, Synthesis and anticancer effects of some novel 2-(4-phenoxyphenyl)-1H-benzimidazole derivatives on K562 cell line Archives of Pharmacal Research. ,vol. 38, pp. 650- 658 ,(2015) , 10.1007/S12272-014-0438-X

Marcus Baumann, Ian R Baxendale, Steven V Ley, Nikzad Nikbin, An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals. Beilstein Journal of Organic Chemistry. ,vol. 7, pp. 442- 495 ,(2011) , 10.3762/BJOC.7.57

Jeremy M. Praetorius, Ruiyao Wang, Cathleen M. Crudden, Benzimidazoles as Ligands in the Ruthenium-Catalyzed Enantioselective Bifunctional Hydrogenation of Ketones Organometallics. ,vol. 29, pp. 554- 561 ,(2010) , 10.1021/OM900897B

Shi-Kai Xiang, Wen Tan, Dong-Xue Zhang, Xian-Li Tian, Chun Feng, Bi-Qin Wang, Ke-Qing Zhao, Ping Hu, Hua Yang, Synthesis of benzimidazoles by potassium tert-butoxide-promoted intermolecular cyclization reaction of 2-iodoanilines with nitriles. Organic and Biomolecular Chemistry. ,vol. 11, pp. 7271- 7275 ,(2013) , 10.1039/C3OB41479E

D. Nageswar Rao, Sk. Rasheed, Ram A. Vishwakarma, Parthasarathi Das, Hypervalent iodine(III) catalyzed oxidative C–N bond formation in water: synthesis of benzimidazole-fused heterocycles RSC Advances. ,vol. 4, pp. 25600- 25604 ,(2014) , 10.1039/C4RA02279C

Haiquan Liu, Jiaming Tang, Liu Jiang, Tingting Zheng, Xiaoxia Wang, Xin Lv, None, Efficient domino synthesis of benzimidazole derivatives: copper catalysis versus transition metal-free conditions Tetrahedron Letters. ,vol. 56, pp. 1624- 1630 ,(2015) , 10.1016/J.TETLET.2015.01.197

Hao-Bing Yu, Fan Yang, Fan Sun, Jing Li, Wei-Hua Jiao, Jian-Hong Gan, Wen-Zhen Hu, Hou-Wen Lin, Aaptamine derivatives with antifungal and anti-HIV-1 activities from the South China Sea sponge Aaptos aaptos. Marine Drugs. ,vol. 12, pp. 6003- 6013 ,(2014) , 10.3390/MD12126003

Guodong Yuan, Haiquan Liu, Jilong Gao, Hongjuan Xu, Liu Jiang, Xiaoxia Wang, Xin Lv, An efficient and facile synthesis of benzimidazo[1,2-a]benzimidazoles via copper-catalyzed domino addition/double cyclization RSC Advances. ,vol. 4, pp. 21904- 21908 ,(2014) , 10.1039/C4RA01181C