Intestinal Anti-Inflammatory Activity of Lentinan: Influence on IL-8 and TNFR1 Expression in Intestinal Epithelial Cells

作者: Yosuke Nishitani , Ling Zhang , Masaru Yoshida , Takeshi Azuma , Kazuki Kanazawa

DOI: 10.1371/JOURNAL.PONE.0062441

关键词: LentinanInterleukinTumor necrosis factor alphaIntestinal mucosaColitisImmune systemInflammationImmunologyCancer researchInterleukin 8ChemistryGeneral Biochemistry, Genetics and Molecular BiologyGeneral Agricultural and Biological SciencesGeneral Medicine

摘要: … effect on intestinal inflammation induced by dietary β-1,3;1,6-glucan will provide valuable information toward the establishment of a new β-glucan therapy for treating patients with IBD. …

参考文章(54)
Makoto Naganuma, Toshifumi Hibi, Haruhiko Ogata, Nagamu Inoue, Introduction and overview: recent advances in the immunotherapy of inflammatory bowel disease. Journal of Gastroenterology. ,vol. 38, pp. 36- 42 ,(2003)
Futoshi Arai, Toru Takahashi, Koichi Furukawa, Kouji Matsushima, Hitoshi Asakura, Mucosal Expression of Interleukin-6 and Interleukin-8 Messenger RNA in Ulcerative Colitis and in Crohn's Disease Digestive Diseases and Sciences. ,vol. 43, pp. 2071- 2079 ,(1998) , 10.1023/A:1018815432504
Li Liu, Zhi-Peng Wang, Chang-Tai Xu, Bo-Rong Pan, Qi-Bing Mei, Yin Long, Jia-Yun Liu, Si-Yuan Zhou, Effects ofRheum tanguticumpolysaccharide on TNBS -induced colitis and CD4+T cells in rats World Journal of Gastroenterology. ,vol. 9, pp. 2284- 2288 ,(2003) , 10.3748/WJG.V9.I10.2284
Mehri Zareie, Paramjit K. Singh, E. Jan Irvine, Philip M. Sherman, Derek M. McKay, Mary H. Perdue, Monocyte/Macrophage Activation by Normal Bacteria and Bacterial Products The American Journal of Pathology. ,vol. 158, pp. 1101- 1109 ,(2001) , 10.1016/S0002-9440(10)64057-6
Craig Gerard, Barrett J. Rollins, Chemokines and disease Nature Immunology. ,vol. 2, pp. 108- 115 ,(2001) , 10.1038/84209
William E. Pullman, Susan Elsbury, Masanobu Kobayashi, Andrew J. Hapel, William F. Doe, Enhanced Mucosal Cytokine Production in Inflammatory Bowel Disease Gastroenterology. ,vol. 102, pp. 529- 537 ,(1992) , 10.1016/0016-5085(92)90100-D
R H Rolandelli, S H Saul, R G Settle, D O Jacobs, S O Trerotola, J L Rombeau, Comparison of parenteral nutrition and enteral feeding with pectin in experimental colitis in the rat The American Journal of Clinical Nutrition. ,vol. 47, pp. 715- 721 ,(1988) , 10.1093/AJCN/47.4.715
Rana Al-Sadi, Dongmei Ye, Karol Dokladny, Thomas Y. Ma, Mechanism of IL-1β-Induced Increase in Intestinal Epithelial Tight Junction Permeability Journal of Immunology. ,vol. 180, pp. 5653- 5661 ,(2008) , 10.4049/JIMMUNOL.180.8.5653
Shizuo Akira, Toshio Hirano, Tetsuya Taga, Tadamitsu Kishimoto, Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF) The FASEB Journal. ,vol. 4, pp. 2860- 2867 ,(1990) , 10.1096/FASEBJ.4.11.2199284
Liyan Zhang, Nan Li, Ricardo Caicedo, Josef Neu, Alive and Dead Lactobacillus rhamnosus GG Decrease Tumor Necrosis Factor-α–Induced Interleukin-8 Production in Caco-2 Cells Journal of Nutrition. ,vol. 135, pp. 1752- 1756 ,(2005) , 10.1093/JN/135.7.1752