Bicarbonate dialysis compared to hemodiafiltration on glycemic excursions in patients with end-stage renal disease with and without type 2 diabetes mellitus

摘要: Abstract Aim To evaluate the effects on glycemic excursions during bicarbonate dialysis (BHD) compared to hemodiafiltration (HDF) in type 2 diabetic or not patients affected by end-stage renal disease (ESRD). Material and Methods Thirty-six (20 diabetes mellitus, 16 patients) were evaluated underwent BHD dialysis, followed HDF two days later. All also glucose continuous monitoring system, using i Pro Continuous Glucose Monitor System (Medtronic MiniMed) starting just before BHD, ending five later, after dialysis. Glycemic control was estimated as mean blood (MBG), area under curve above 70mg/dl (AUC >70 ) 180mg/dl >180 ), percentage of time (t ). Intraday variability assessed standard deviation (SD), M value, amplitude (MAGE). Day-to-day daily difference (MODD), that is absolute among values taken consecutive at same time. Results better with HDF: MBG, AUC lower do BHD. We observed a significant decrease dialysis: SD, MAGE value HDF. The MODD significantly changed group, while no differences recorded Conclusion seems greater reduce treatment