Ambulatory 24-hour blood pressure monitoring: correlation between blood pressure variability and left ventricular hypertrophy in untreated hypertensive patients.

摘要: BACKGROUND Left ventricular hypertrophy (LVH) appears to be poorly correlated with clinical measurements of blood pressure: a better correlation may observed data from 24 h ambulatory pressure monitoring (ABPM). The aim this study was compare the results non-invasive ABPM in population patients essential hypertension who had never been treated, subdividing them based on presence or absence LVH transthoracic echocardiogram (LVMI, left mass index > 135 g/m2 males and 110 females). METHODS Eighty hypertensive mild moderate underwent routine tests, echocardiogram. Based ABPMs, we analyzed average systolic diastolic (BP), daytime (6 a.m.-10 p.m.) nighttime (10 p.m.-6 a.m.) BP, morning (6-12 BP number dipper non-dipper patients. echocardiographic included calculation using Devereux's formula according Penn convention, analysis patterns geometry function. RESULTS Thirty-five (43.7%) at study. In 52 subjects, history showed least one measurement 140/90 mmHg year prior our observation. age 48 +/- 11, without any significant LVMI (r = 0.13). magnitude S-wave V1 R-wave V5 tallest electrocardiogram 0.23 r 0.26, respectively). revealed normal 43.8% patients, concentric remodeling 13.8%, 16.2% eccentric 26.2%. isovolumic relaxation time (IVRT) A-wave were significantly 0.49 0.33, (24 0.34; 0.35; 0.28; 6-12 0.29) but not BP. Dipper represented 76.3% population, difference between dippers non-dippers (p 0.09). higher prevalence ventricles as compared < 0.0001). White-coat 7.5% CONCLUSIONS high some parameters related function (IVRT, A-wave) LVMI. Systolic LVMI, while not.