Cross-species comparison of conazole fungicide metabolites using rat and rainbow trout (Onchorhynchus mykiss) hepatic microsomes and purified human CYP 3A4.

作者: Christopher S. Mazur , John F. Kenneke

DOI: 10.1021/ES072049B

关键词: TroutCytochrome P450MicrosomeMetaboliteMonooxygenaseRainbow troutBiochemistryMetabolic pathwayBiologyXenobiotic

摘要: … A slightly different hexaconazole metabolic profile was observed with the detection of Hex-M3 and M4 in trout microsome systems, whereas neither was detected in the rat. Trace level …

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