Milk Fat Globule Membrane Ameliorates Necrotizing Enterocolitis in Neonatal Rats and Suppresses Lipopolysaccharide-Induced Inflammatory Response in IEC-6 Enterocytes.
作者： Dandan Zhang , Jie Wen , Jiefei Zhou , Wei Cai , Linxi Qian
DOI: 10.1002/JPEN.1496
关键词: Lipopolysaccharide 、 TLR4 、 Receptor 、 Enterocyte 、 Internal medicine 、 Chemistry 、 Endocrinology 、 Apoptosis 、 Inflammation 、 Oxidative stress 、 Necrotizing enterocolitis
摘要: … Meanwhile, lipopolysaccharide (LPS)-stimulated IEC-6 enterocytes were used as a model … cultured IEC-6 cells simulated by LPS. As shown in Figure 4A, different concentrations of LPS (…
sci-hub.se 参考文章(38)
Fan Yang, Eric Tang, Kunliang Guan, Cun-Yu Wang, IKKβ Plays an Essential Role in the Phosphorylation of RelA/p65 on Serine 536 Induced by Lipopolysaccharide Journal of Immunology. ,vol. 170, pp. 5630- 5635 ,(2003) , 10.4049/JIMMUNOL.170.11.5630
Md. Monowar Aziz, Shunji Ishihara, Yoshiyuki Mishima, Naoki Oshima, Ichiro Moriyama, Takafumi Yuki, Yasunori Kadowaki, Mohammad Azharul Karim Rumi, Yuji Amano, Yoshikazu Kinoshita, MFG-E8 Attenuates Intestinal Inflammation in Murine Experimental Colitis by Modulating Osteopontin-Dependent αvβ3 Integrin Signaling Journal of Immunology. ,vol. 182, pp. 7222- 7232 ,(2009) , 10.4049/JIMMUNOL.0803711
Steven C. Gribar, Chhinder P. Sodhi, Ward M. Richardson, Rahul J. Anand, George K. Gittes, Maria F. Branca, Adam Jakub, Xia-hua Shi, Sohail Shah, John A. Ozolek, David J. Hackam, Reciprocal Expression and Signaling of TLR4 and TLR9 in the Pathogenesis and Treatment of Necrotizing Enterocolitis Journal of Immunology. ,vol. 182, pp. 636- 646 ,(2009) , 10.4049/JIMMUNOL.182.1.636
Christelle Lopez, Chantal Cauty, Fanny Guyomarc’h, Organization of lipids in milks, infant milk formulas and various dairy products: role of technological processes and potential impacts Dairy Science & Technology. ,vol. 95, pp. 863- 893 ,(2015) , 10.1007/S13594-015-0263-0
Nanda Nanthakumar, Di Meng, Allan M. Goldstein, Weishu Zhu, Lei Lu, Ricardo Uauy, Adolfo Llanos, Erika C. Claud, W. Allan Walker, The Mechanism of Excessive Intestinal Inflammation in Necrotizing Enterocolitis: An Immature Innate Immune Response PLoS ONE. ,vol. 6, pp. e17776- ,(2011) , 10.1371/JOURNAL.PONE.0017776
Sheng-Ru Shiou, Yueyue Yu, Yuee Guo, Maria Westerhoff, Lei Lu, Elaine O. Petrof, Jun Sun, Erika C. Claud, Oral Administration of Transforming Growth Factor-β1 (TGF-β1) Protects the Immature Gut from Injury via Smad Protein-dependent Suppression of Epithelial Nuclear Factor κB (NF-κB) Signaling and Proinflammatory Cytokine Production Journal of Biological Chemistry. ,vol. 288, pp. 34757- 34766 ,(2013) , 10.1074/JBC.M113.503946
Bohuslav Dvorak, Melissa D Halpern, Hana Holubec, Katerina Dvorakova, Jessica A Dominguez, Catherine S Williams, Yolanda G Meza, Hana Kozakova, Robert S McCuskey, Maternal milk reduces severity of necrotizing enterocolitis and increases intestinal IL-10 in a neonatal rat model Pediatric Research. ,vol. 53, pp. 426- 433 ,(2003) , 10.1203/01.PDR.0000050657.56817.E0
M. Fukata, M.T. Abreu, TLR4 signalling in the intestine in health and disease. Biochemical Society Transactions. ,vol. 35, pp. 1473- 1478 ,(2007) , 10.1042/BST0351473
Yinzhong Zhang, Max Brenner, Weng-Lang Yang, Ping Wang, Recombinant human MFG-E8 ameliorates colon damage in DSS- and TNBS-induced colitis in mice Laboratory Investigation. ,vol. 95, pp. 480- 490 ,(2015) , 10.1038/LABINVEST.2015.32
Guozhu Yang, Pingqian Bao, Lie Zhang, Zhaoying Lyu, Bin Zhou, Keling Chen, Su Peng, Yi Wang, Longpei Yao, Yin Zhou, Yuan Li, Critical role of myeloid differentiation factor 88 in necrotizing enterocolitis Pediatric Research. ,vol. 75, pp. 707- 715 ,(2014) , 10.1038/PR.2014.39