miRNA-197 and miRNA-184 are associated with brain metastasis in EGFR-mutant lung cancers
作者： J. Remon , D. Alvarez-Berdugo , M. Majem , T. Moran , N. Reguart
DOI: 10.1007/S12094-015-1347-2
关键词: Non small cell 、 Oncology 、 Internal medicine 、 Brain metastasis 、 Lung cancer 、 Cancer 、 Lung 、 Mutant 、 Egfr tki 、 Medicine 、 microRNA
摘要: Introduction The prognostic value of EGFR mutation in lung cancer patients with brain metastases is uncertain and therapeutic efficacy TKI limited. Looking for biomarkers closely related early tumor changes non-small cell warranted. MicroRNAs (miRNAs) are frequently deregulated cancer. The objective this study was to investigate whether some miRNAs metastasis risk EGFR-mutant patients.
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Shin Hamada, Kennichi Satoh, Shin Miura, Morihisa Hirota, Atsushi Kanno, Atsushi Masamune, Kazuhiro Kikuta, Kiyoshi Kume, Jun Unno, Shinichi Egawa, Fuyuhiko Motoi, Michiaki Unno, Tooru Shimosegawa, miR-197 induces epithelial-mesenchymal transition in pancreatic cancer cells by targeting p120 catenin. Journal of Cellular Physiology. ,vol. 228, pp. 1255- 1263 ,(2013) , 10.1002/JCP.24280
Zhen Liu, Chunping Mai, Huiling Yang, Yan Zhen, Xiaoli Yu, Shengni Hua, Qiangyun Wu, Qinping Jiang, Yajie Zhang, Xin Song, Weiyi Fang, Candidate tumour suppressor CCDC19 regulates miR-184 direct targeting of C-Myc thereby suppressing cell growth in non-small cell lung cancers. Journal of Cellular and Molecular Medicine. ,vol. 18, pp. 1667- 1679 ,(2014) , 10.1111/JCMM.12317
Stephanie Heon, Beow Y. Yeap, Gregory J. Britt, Daniel B. Costa, Michael S. Rabin, David M. Jackman, Bruce E. Johnson, Development of central nervous system metastases in patients with advanced non-small cell lung cancer and somatic EGFR mutations treated with gefitinib or erlotinib. Clinical Cancer Research. ,vol. 16, pp. 5873- 5882 ,(2010) , 10.1158/1078-0432.CCR-10-1588
Akimasa Sekine, Terufumi Kato, Eri Hagiwara, Takeshi Shinohara, Takanobu Komagata, Tae Iwasawa, Hiroaki Satoh, Katsumi Tamura, Tomotaka Kasamatsu, Kenji Hayashihara, Takefumi Saito, Hiroshi Takahashi, Takashi Ogura, Metastatic brain tumors from non-small cell lung cancer with EGFR mutations: Distinguishing influence of exon 19 deletion on radiographic features Lung Cancer. ,vol. 77, pp. 64- 69 ,(2012) , 10.1016/J.LUNGCAN.2011.12.017
Noemi Reguart, Jordi Remon, Common EGFR-mutated subgroups (Del19/L858R) in advanced non-small-cell lung cancer: chasing better outcomes with tyrosine kinase inhibitors Future Oncology. ,vol. 11, pp. 1245- 1257 ,(2015) , 10.2217/FON.15.15
Liqin Du, Jeoffrey J. Schageman, Maria C. Subauste, Barbara Saber, Scott M. Hammond, Ludmila Prudkin, Ignacio I. Wistuba, Lin Ji, Jack A. Roth, John D. Minna, Alexander Pertsemlidis, miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1 Molecular Cancer Research. ,vol. 7, pp. 1234- 1243 ,(2009) , 10.1158/1541-7786.MCR-08-0507
Christoph Pöttgen, Wilfried Eberhardt, Andreas Grannass, Soenke Korfee, Georg Stüben, Helmut Teschler, Georgios Stamatis, Horst Wagner, Bernward Passlick, Volker Petersen, Volker Budach, Hans Wilhelm, Isabel Wanke, Herbert Hirche, Hans-Jochen Wilke, Martin Stuschke, Prophylactic Cranial Irradiation in Operable Stage IIIA Non–Small-Cell Lung Cancer Treated With Neoadjuvant Chemoradiotherapy: Results From a German Multicenter Randomized Trial Journal of Clinical Oncology. ,vol. 25, pp. 4987- 4992 ,(2007) , 10.1200/JCO.2007.12.5468
Stephanie Heon, Beow Y. Yeap, Neal I. Lindeman, Victoria A. Joshi, Mohit Butaney, Gregory J. Britt, Daniel B. Costa, Michael S. Rabin, David M. Jackman, Bruce E. Johnson, The Impact of Initial Gefitinib or Erlotinib versus Chemotherapy on Central Nervous System Progression in Advanced Non–Small Cell Lung Cancer with EGFR Mutations Clinical Cancer Research. ,vol. 18, pp. 4406- 4414 ,(2012) , 10.1158/1078-0432.CCR-12-0357
Jingjing Liu, Xu Wang, Xiaoning Yang, Yunpeng Liu, Ying Shi, Jianlin Ren, Bayasi Guleng, miRNA423-5p regulates cell proliferation and invasion by targeting trefoil factor 1 in gastric cancer cells Cancer Letters. ,vol. 347, pp. 98- 104 ,(2014) , 10.1016/J.CANLET.2014.01.024
Petra Hoffknecht, Amanda Tufman, Thomas Wehler, Theo Pelzer, Rainer Wiewrodt, Martin Schütz, Monika Serke, Jan Stöhlmacher-Williams, Angela Märten, Rudolf Maria Huber, Nicolas J Dickgreber, Afatinib Compassionate Use Consortium, None, Efficacy of the Irreversible ErbB Family Blocker Afatinib in Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI)–Pretreated Non–Small-Cell Lung Cancer Patients with Brain Metastases or Leptomeningeal Disease Journal of Thoracic Oncology. ,vol. 10, pp. 156- 163 ,(2015) , 10.1097/JTO.0000000000000380