Mercury Toxicity and the Mitigating Role of Selenium

摘要: Mercury is a well-known environmental toxicant, particularly in its most common organic form, methylmercury. Consumption of fish and shellfish that contain methylmercury dominant source mercury exposure humans piscivorous wildlife. Considerable efforts have focused on assessment attendant risks the environment food sources, including studies reported this issue. However, intoxication frequently failed to consider protective effects essential trace element, selenium. binds selenium with extraordinarily high affinity, maternal exposures inhibit selenium-dependent enzyme activities fetal brains. increased dietary intakes preserve these activities, thereby preventing pathological would otherwise arise their absence. Recent evidence indicates assessments tissue levels need distributions order provide meaningful risk evaluations.