Serum Fetuin-A Levels in Patients with Cardiovascular Disease: A Meta-Analysis
作者： Ze-Lin Sun , Qi-Ying Xie , Gong-Liang Guo , Ke Ma , Yuan-Yuan Huang
DOI: 10.1155/2014/691540
关键词: Meta-analysis 、 Knowledge infrastructure 、 Insulin resistance 、 alpha-2-HS-glycoprotein 、 Bioinformatics 、 Cochrane Library 、 Disease 、 Internal medicine 、 Fetuin 、 Medicine 、 In patient
摘要: Background. Fetuin-A (FA) suppresses arterial calcification, promotes insulin resistance, and appears to be elevated in patients with cardiovascular diseases (CVD), but the data is still inconsistent. To clarify correlation between serum FA levels presence severity of CVDs, we performed this meta-analysis. Method. Potential relevant studies were identified covering following databases: PubMed, Embase, Web Science, Cochrane Library, CISCOM, CINAHL, Google Scholar, China BioMedicine (CBM), National Knowledge Infrastructure (CNKI) databases. Data from eligible extracted included meta-analysis using a random-effects model. Results. Ten case-control studies, including 1,281 CVDs 2,663 healthy controls, included. The results showed significant differences controls (SMD = 1.36, 95%CI: 0.37–2.36, ). Ethnicity-subgroup analysis implied that low are related Caucasians (SMD = 1.73, 0.20–3.26, ), not Asians 1.04, −0.33–2.40, Conclusion. indicated decreased level correlated development CVDs. might clinically valuable for reflecting progression
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