Linear Spatially Encoded Combinatorial Chemistry with Fourier Transform Library Analysis

摘要: An effective combinatorial chemical technique must facilitate all aspects of the experiment, including synthesis, Assay, and association structure with activity; it also provide output data in a usable form. The best applied to given study depends on many factors, availability high-throughput assay critical choice library size. It is important distinguish between experiments where target substance, And those information sought. A selection scheme subsequent decoding active compounds appropriate when searching for while spatially encoded procedure which members are identified can potentially more information.