Cancer chemotherapy reduces plasma total antioxidant capacity in children with malignancies
作者： Maria Papageorgiou , Eftichia Stiakaki , Helen Dimitriou , Niki Malliaraki , George Notas
DOI: 10.1016/J.LEUKRES.2004.04.017
关键词: Immunology 、 Chemotherapy 、 Reactive oxygen species 、 Malignancy 、 Pharmacology 、 Prospective cohort study 、 Endogeny 、 Medicine 、 Flow cytometry 、 In vivo 、 Extracellular fluid
摘要: The sum of endogenous and food-derived antioxidants provides an estimate the total antioxidant capacity (TAC) extracellular fluids, while corrected TAC (cTAC) is estimation exogenously provided antioxidants. Similar values for cTAC were observed between cancer free children with malignancy at diagnosis. Antineoplastic treatment induced a significant decrease during chemotherapy. Additionally to dietary factors, this might be attributed antineoplastic drugs as shown by increase ROS after administration chemotherapeutic agents both in vitro vivo. According our preliminary results returned normal end therapy.
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sci-hub.se 参考文章(31)
A. Lupulescu, Ultrastructure and cell surface studies of cancer cells following vitamin C administration. Experimental and Toxicologic Pathology. ,vol. 44, pp. 3- 9 ,(1992) , 10.1016/S0940-2993(11)80129-6
Brignall Ms, Lamson Dw, Antioxidants in cancer therapy; their actions and interactions with oncologic therapies. Alternative medicine review : a journal of clinical therapeutic. ,vol. 4, pp. 304- ,(1999)
Andrew N Margioris, Elias Castanas, Niki Malliaraki, Dimitris Mpliamplias, Marilena Kampa, Kostas Perakis, Total and corrected antioxidant capacity in hemodialyzed patients. BMC Nephrology. ,vol. 4, pp. 4- 4 ,(2003) , 10.1186/1471-2369-4-4
Gregor Rhote, Günter Valet, [56] Flow cytometric assays of oxidative burst activity in phagocytes Methods in Enzymology. ,vol. 233, pp. 539- 548 ,(1994) , 10.1016/S0076-6879(94)33059-X
Mammo Amare, Chan H. Park, Michael A. Savin, Barth Hoogstraten, Growth suppression of human leukemic cells in vitro by L-ascorbic acid. Cancer Research. ,vol. 40, pp. 1062- 1065 ,(1980)
Kenneth A. Conklin, Dietary antioxidants during cancer chemotherapy: impact on chemotherapeutic effectiveness and development of side effects. Nutrition and Cancer. ,vol. 37, pp. 1- 18 ,(2000) , 10.1207/S15327914NC3701_1
J S Carew, Y Zhou, M Albitar, J D Carew, M J Keating, Peng Huang, Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications. Leukemia. ,vol. 17, pp. 1437- 1447 ,(2003) , 10.1038/SJ.LEU.2403043
Kedar N. Prasad, Christine Hernandez, Judith Edwards‐Prasad, Joan Nelson, Todd Borus, William A. Robinson, Modification of the effect of tamoxifen, cis-platin, DTIC, and interferon-α2b on human melanoma cells in culture by a mixture of vitamins Nutrition and Cancer. ,vol. 22, pp. 233- 245 ,(1994) , 10.1080/01635589409514349
Mary E. Kerr, Catherine M. Bender, Elizabeth J. Monti, An introduction to oxygen free radicals Heart & Lung. ,vol. 25, pp. 200- 209 ,(1996) , 10.1016/S0147-9563(96)80030-6
Sema Sentürker, Bensu Karahalil, Mine Inal, Hülya Yilmaz, Hamza Müslümanoglu, Gündüz Gedikoglu, Miral Dizdaroglu, None, Oxidative DNA base damage and antioxidant enzyme levels in childhood acute lymphoblastic leukemia FEBS Letters. ,vol. 416, pp. 286- 290 ,(1997) , 10.1016/S0014-5793(97)01226-X