The effects of salbutamol aerosol on lung function in patients with pulmonary emphysema

作者: D. Bellamy , D.C.S. Hutchinson

DOI: 10.1016/0007-0971(81)90052-8

关键词: Lung functionBronchodilatorIn patientSalbutamolInhalerDouble blindAnesthesiaMedicinePlaceboPulmonary emphysema

摘要: Abstract The effects of inhaling 400 μg salbutamol were compared with identical placebo inhaler in a double blind cross-over study 20 patients radiological evidence pulmonary emphysema. There was small but significant rise the forced expiratory volume one second (FEV 1 ), there much greater increase vital capacity (VC), which accompanied by reduction residual volume. Symptomatic improvement after reported 14 and VC increased significantly this group; no who did not prefer active inhaler. consistent change FEV /VC ratio administration is misleading as an indicator bronchodilator responsiveness Salbutamol thus valuable addition to treatment emphysema response best judged measuring VC.

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