作者: D. Bellamy , D.C.S. Hutchinson
DOI: 10.1016/0007-0971(81)90052-8
关键词: Lung function 、 Bronchodilator 、 In patient 、 Salbutamol 、 Inhaler 、 Double blind 、 Anesthesia 、 Medicine 、 Placebo 、 Pulmonary emphysema
摘要: Abstract The effects of inhaling 400 μg salbutamol were compared with identical placebo inhaler in a double blind cross-over study 20 patients radiological evidence pulmonary emphysema. There was small but significant rise the forced expiratory volume one second (FEV 1 ), there much greater increase vital capacity (VC), which accompanied by reduction residual volume. Symptomatic improvement after reported 14 and VC increased significantly this group; no who did not prefer active inhaler. consistent change FEV /VC ratio administration is misleading as an indicator bronchodilator responsiveness Salbutamol thus valuable addition to treatment emphysema response best judged measuring VC.