Executive function impairments in depression and bipolar disorder: association with functional impairment and quality of life

作者: Charles Cotrena , Laura Damiani Branco , Flávio Milman Shansis , Rochele Paz Fonseca

DOI: 10.1016/J.JAD.2015.11.007

关键词: NeurocognitiveBipolar disorderPsychiatryClinical psychologyNeuropsychologyMajor depressive disorderPsychologyExecutive functionsStroop effectTrail Making TestQuality of life

摘要: Abstract Background The neuropsychological correlates of major depressive (MDD) and bipolar disorder (BD), their association with quality life (QOL) functioning, have not been sufficiently studied in the literature. present study aimed to compare executive functions, attention, processing speed, QOL disability between patients BD type I, II, MDD healthy controls. Method: 205 participants (n=37 BDI, 81% female; n=35 BDII, 80% n=45 MDD, 69% n=89C, 46% female) aged 18 67 years were administered an extensive neurocognitive battery consisting widely used standardized measures such as Trail Making Test, Stroop Color-Word Test a modified version Wisconsin Card Sorting Task. Z-scores compared groups by ANCOVA. prevalence impairments on each measure (Z-score

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