Efficacy of Blood-Patch Pleurodesis for Secondary Spontaneous Pneumothorax in Interstitial Lung Disease

摘要: Objective We identified the prognostic relevance of pneumothorax in interstitial lung disease (ILD) patients and evaluated efficacy safety autologous blood-patch pleurodesis. Methods retrospectively reviewed 59 occurrences 34 ILD over a 12-year period. Results Air leakage ceased 16 22 (72.7%) episodes after blood pleurodesis 11 14 (78.6%) chemical Both cure ratio recurrence were comparable with those group (p=0.99 0.99, respectively). In addition, there no harmful events associated The median survival time first episode was less than 9 months idiopathic pneumonia (IIP) only around 3 years other types ILD, which have essentially favorable outcomes. Kaplan-Meier estimates significantly worse concomitant pneumomediastinum without (p<0.05). A multivariate Cox regression analysis that number pneumothorax, IIP diagnosis independent predictors death. Conclusion Autologous is safe worth considering as first-line treatment for secondary to ILD. However, despite treatments, prognosis onset found be poor. may further worsen prognosis.