关键词: Renal function 、 Kidney 、 Muscle hypertrophy 、 Urology 、 Kidney Volume 、 Internal medicine 、 Medicine 、 Glomerular hyperfiltration 、 Kidney development 、 Endocrinology 、 Nephron 、 Albuminuria
摘要: The growing prevalence of CKD across the world has intensified search for factors responsible progressive loss kidney function over time. In 1980s, Brenner et al. reported that reduced nephron number results in glomerular hyperfiltration and hypertrophy, leading to maladaptive further