Is microalbuminuria a risk factor for hypertension in children with solitary kidney
作者： Nurdan Yildiz , Nese Biyikli , Seyfettin Ustunsoy , Meryem Benzer , Harika Alpay
DOI: 10.1007/S00467-013-2641-2
关键词: Endocrinology 、 Renal function 、 Creatinine 、 Dimercaptosuccinic acid 、 Microalbuminuria 、 Internal medicine 、 Ambulatory blood pressure 、 Medicine 、 Urology 、 Cystatin C 、 Urinary system 、 Urine
摘要: The correlations between ambulatory blood pressure measurements (ABPM) and serum cystatin C (Cys C), creatinine (Cr), microalbumin (MA), β2-microglobulin (β2-MG) levels in 24 h (24-h) urine were analyzed children with solitary kidney (SK) compared to healthy children. Fifty normal functioning SK 25 controls studied. ABPM, Cys C, Cr, MA, β2-MG 24-h measured all Clinical symptoms signs, laboratory results, urinary ultrasonography, voiding cystourethrography, Dimercaptosuccinic acid (DMSA) scintigraphy results recorded the group. Four patients Wilms’ tumor two renal scarring excluded from study. mean ages of group 9.6 ± 3.6 9.3 ± 3.3 years, respectively. Cr levels, MA similar both groups (p > 0.05). However, excretion was higher living more than 5 years (p = 0.01). Standard deviation scores ABPM parameters showed no significant correlation groups. Children have increased long term, need prolonged follow-up detect early deterioration function prevent end-organ damage later life.
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sci-hub.se 参考文章(40)
Colvin Rb, Kiprov Dd, McCluskey Rt, Focal and Segmental Glomerulosclerosis and Porteinuria Associated With Unilateral Renal Agenesis Laboratory Investigation. ,vol. 46, pp. 275- ,(1982)
G. B. Haycock, G. J. Schwartz, Adrian Spitzer, C. M. Edelmann, A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine Pediatrics. ,vol. 58, pp. 259- 263 ,(1976)
Pietro Zucchelli, Leonardo Cagnoli, Silvia Casanova, Ugo Donini, Sonia Pasquali, Focal glomerulosclerosis in patients with unilateral nephrectomy Kidney International. ,vol. 24, pp. 649- 655 ,(1983) , 10.1038/KI.1983.207
Olcay Neyzi, Andrzej Furman, Ruveyde Bundak, Hulya Gunoz, Feyza Darendeliler, Firdevs Bas, None, Growth references for Turkish children aged 6 to 18 years Acta Paediatrica. ,vol. 95, pp. 1635- 1641 ,(2006) , 10.1080/08035250600652013
Ingrid Wikstad, Gianni Celsi, Lars Larsson, Peter Herin, Anita Aperia, Kidney function in adults born with unilateral renal agenesis or nephrectomized in childhood Pediatric Nephrology. ,vol. 2, pp. 177- 182 ,(1988) , 10.1007/BF00862585
Bertram L. Kasiske, Jennie Z. Ma, Thomas A. Louis, Suzanne K. Swan, Long-term effects of reduced renal mass in humans Kidney International. ,vol. 48, pp. 814- 819 ,(1995) , 10.1038/KI.1995.355
Grażyna Krzemień, Maria Roszkowska-Blaim, Izabella Kostro, Julita Wojnar, Monika Karpińska, Renata Sękowska, Urological anomalies in children with renal agenesis or multicystic dysplastic kidney. Journal of Applied Genetics. ,vol. 47, pp. 171- 176 ,(2006) , 10.1007/BF03194618
Raymond M. Hakim, Robert C. Goldszer, Barry M. Brenner, Hypertension and proteinuria: Long-term sequelae of uninephrectomy in humans Kidney International. ,vol. 25, pp. 930- 936 ,(1984) , 10.1038/KI.1984.112
Michio Nagata, Karl Schärer, Wilhelm Kriz, Glomerular damage after uninephrectomy in young rats. I. Hypertrophy and distortion of capillary architecture Kidney International. ,vol. 42, pp. 136- 147 ,(1992) , 10.1038/KI.1992.271
Tomáš Seeman, Ludwig Patzer, Ulrike John, Jiří Dušek, Karel Vondrák, Jan Janda, Joachim Misselwitz, Blood pressure, renal function, and proteinuria in children with unilateral renal agenesis. Kidney & Blood Pressure Research. ,vol. 29, pp. 210- 215 ,(2006) , 10.1159/000095735