A new method for the preparation of Δ2-isoxazolin-5-ones from the oximes of ketones having an α-hydrogen atom

作者： Jonathan S. Griffiths , Charles F. Beam , Charles R. Hauser

关键词: Crystallography 、 Hydrogen atom 、 Chemistry 、 Atom (order theory) 、 Stereochemistry 、 Hydrogen atom abstraction 、 Organic chemistry

摘要: Certain oximes having an α-hydrogen atom were treated with n-butyl-lithium (2 mol.equiv.) to give the 1,4-dianions, which carbonated and acid-cyclized Δ2-isoxazolin-5-ones.