Preparation of 2‐isoxazolines from C(α),O‐dilithiooximes and aldehydes and ketones
作者： Charles A. Park , Charles F. Beam , Edwin M. Kaiser , Robert J. Kaufman , Fred E. Henoch
关键词: Combinatorial chemistry 、 Condensation 、 Organic chemistry 、 Chemistry
摘要: C(α),O-Dilithiooximes were condensed with aldehydes and ketones to give β-hydroxyoximes which usually isolated characterized. These materials could be acid-cyclized the 2-isoxazoline. When dianion was p-anisaldehyde, it not necessary isolate intermediate; direct acid-cyclization after condensation led
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