Preparation of 2,4‐diarylquinolines and substituted dihydrobenz‐[c]acridines by the condensation of certain c(α),o‐dilithiooximes with 2‐aminobenzophenones
作者： Dorothy J. Park , Tammy D. Fulmer , Charles F. Beam
关键词: Medicinal chemistry 、 Lithium diisopropylamide 、 Condensation 、 Dehydration 、 Diarylquinolines 、 Stereochemistry 、 Chemistry 、 Acid hydrolysis
摘要: C(α),O-Dilithiooximes were prepared in an excess of lithium diisopropylamide and condensed with several 2-aminobenzophenones, followed by acid hydrolysis the oximes to ketones, which then underwent cyclodehydration linear dehydration give substituted quinolines or dihydrobenz[c]acridines.
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