Alcohol effects on cardiac function.

作者: Jason D. Gardner , Alan J. Mouton

DOI: 10.1002/CPHY.C140046

关键词: Heart failureCardiomyopathyInternal medicineAnesthesiaAlcoholCardiac function curvePathophysiologyEthanolCardiologyMedicineAlcohol abuseAlcohol and health

摘要: The consumption of ethanol can have both beneficial and detrimental effects on the function heart cardiovascular system, depending amount consumed. Low-to-moderate amounts intake are associated with improvements in cardiac vascular health. On other hand, chronically consumed large acts as a toxin to vasculature. injury produced by chronic alcohol abuse progress failure eventual death. Furthermore, may exacerbate preexisting conditions, such hypertension cardiomyopathy. This article focuses molecular mechanisms pathophysiology alcohol.

参考文章(109)
Yong Son, Sangduck Kim, Hun-Taeg Chung, Hyun-Ock Pae, Reactive oxygen species in the activation of MAP kinases. Methods in Enzymology. ,vol. 528, pp. 27- 48 ,(2013) , 10.1016/B978-0-12-405881-1.00002-1
Yi Tan, Xiaokun Li, Sumanth D. Prabhu, Kenneth R. Brittian, Qiang Chen, Xia Yin, Craig J. McClain, Zhanxiang Zhou, Lu Cai, Angiotensin II Plays a Critical Role in Alcohol-Induced Cardiac Nitrative Damage, Cell Death, Remodeling, and Cardiomyopathy in a Protein Kinase C/Nicotinamide Adenine Dinucleotide Phosphate Oxidase–Dependent Manner Journal of the American College of Cardiology. ,vol. 59, pp. 1477- 1486 ,(2012) , 10.1016/J.JACC.2011.12.034
James H. O’Keefe, Kevin A. Bybee, Carl J. Lavie, Alcohol and Cardiovascular Health: The Razor-Sharp Double-Edged Sword Journal of the American College of Cardiology. ,vol. 50, pp. 1009- 1014 ,(2007) , 10.1016/J.JACC.2007.04.089
Paul J. Lijnen, Jos F. van Pelt, Robert H. Fagard, Stimulation of reactive oxygen species and collagen synthesis by angiotensin II in cardiac fibroblasts. Cardiovascular Therapeutics. ,vol. 30, ,(2012) , 10.1111/J.1755-5922.2010.00205.X
Heng-Jie Cheng, Kathleen A. Grant, Qing-Hua Han, James B. Daunais, David P. Friedman, Satoshi Masutani, William C. Little, Che-Ping Cheng, Up-Regulation and Functional Effect of Cardiac β3-Adrenoreceptors in Alcoholic Monkeys Alcoholism: Clinical and Experimental Research. ,vol. 34, pp. 1171- 1181 ,(2010) , 10.1111/J.1530-0277.2010.01194.X
A. Toth, B. Sandor, J. Papp, M. Rabai, D. Botor, Zs. Horvath, P. Kenyeres, I. Juricskay, K. Toth, L. Czopf, Moderate red wine consumption improves hemorheological parameters in healthy volunteers. Clinical Hemorheology and Microcirculation. ,vol. 56, pp. 13- 23 ,(2014) , 10.3233/CH-2012-1640
Jerrold H. Levy, Ian Welsby, Lawrence T. Goodnough, Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy. Transfusion. ,vol. 54, pp. 1389- 1405 ,(2014) , 10.1111/TRF.12431
Amabel M. Orogo, Åsa B. Gustafsson, Cell death in the myocardium: my heart won't go on. Iubmb Life. ,vol. 65, pp. 651- 656 ,(2013) , 10.1002/IUB.1180
José Marı́n-Garcı́a, Michael J Goldenthal, Mitochondria play a critical role in cardioprotection. Journal of Cardiac Failure. ,vol. 10, pp. 55- 66 ,(2004) , 10.1016/S1071-9164(03)00129-5
A A Abdel-Rahman, W R Wooles, Ethanol-induced hypertension involves impairment of baroreceptors. Hypertension. ,vol. 10, pp. 67- 73 ,(1987) , 10.1161/01.HYP.10.1.67