Identification of Enriched Driver Gene Alterations in Subgroups of Non-Small Cell Lung Cancer Patients Based on Histology and Smoking Status
作者： She-Juan An , Zhi-Hong Chen , Jian Su , Xu-Chao Zhang , Wen-Zhao Zhong
DOI: 10.1371/JOURNAL.PONE.0040109
关键词: Mutation 、 Carcinogenesis 、 Gene 、 Adenocarcinoma 、 Young adult 、 Histology 、 Medicine 、 Immunology 、 Oncology 、 Survival analysis 、 Lung cancer 、 Internal medicine 、 General Biochemistry, Genetics and Molecular Biology 、 General Agricultural and Biological Sciences 、 General Medicine
摘要: Background Appropriate patient selection is needed for targeted therapies that are efficacious only in patients with specific genetic alterations. We aimed to define subgroups of patients …
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