作者: Raju Jannapu Reddy , Angothu Shankar , Md. Waheed , Jagadeesh Babu Nanubolu
DOI: 10.1016/J.TETLET.2018.04.023
关键词: Regioselectivity 、 Chemistry 、 Reaction conditions 、 Aryl 、 Combinatorial chemistry 、 Metal free 、 Sodium
摘要: Abstract A convenient and metal-free protocol for the highly regioselective sulfonylation of NH-1,2,3-triazoles is described. range readily accessible were sulfonylated with various aryl sulfinates in presence molecular iodine. The scope was extended to thiosulfonates as an efficient sulfonylating agent nitrochromene derived triazoles also explored selective N-sulfonylation. variety synthetically viable N2-sulfonyl obtained moderate high yields excellent regioselectivities via N–S bond construction under mild reaction conditions.