Pathological Review of Wilms Tumor Nephrectomy Specimens and Potential Implications for Nephron Sparing Surgery in Wilms Tumor

摘要: Purpose: Nephron sparing surgery is accepted as standard of care for children with bilateral Wilms tumor or in a solitary kidney and some study protocols allow nephron select cases unilateral tumor. With the increasing use tumor, we reviewed pathological features from radical nephrectomy specimens to determine potential efficacy approach.Materials Methods: Medical records undergoing pre-chemotherapy at our institution were reviewed. Ideal candidates defined those having unifocal mass outside renal hilum, third more kidney, favorable histology, no signs sinus segmental vascular invasion, metastatic lymph nodes gross regional disease, distinct interface on review between remaining parenchyma.Results: A total 78 a...