Advances in Molecular Understanding of α-Helical Membrane-Active Peptides.
作者： Robert Vácha , Robert Vácha , Ivo Kabelka , Ivo Kabelka
DOI: 10.1021/ACS.ACCOUNTS.1C00047
关键词: Membrane 、 Transmembrane protein 、 Amino acid 、 Chemistry 、 Peptide 、 Magainin 、 Phospholipid 、 Antimicrobial peptides 、 Biophysics 、 Cellular compartment
摘要: … that govern the activity of membrane-active peptides. We focus on … Helical segments are represented as cylinders. Hydrophilic/… through biological barriers to improve their bioavailability. …
acs.org
sci-hub.st 参考文章(70)
Victor Nizet, Antimicrobial peptide resistance mechanisms of human bacterial pathogens. Current Issues in Molecular Biology. ,vol. 8, pp. 11- 26 ,(2006)
W. B. Guggino, B. L. Smith, P. Agre, Jin Sup Jung, G. M. Preston, Molecular structure of the water channel through aquaporin CHIP. The hourglass model. Journal of Biological Chemistry. ,vol. 269, pp. 14648- 14654 ,(1994) , 10.1016/S0021-9258(17)36674-7
Donald Voet, Judith G. Voet, Charlotte W. Pratt, Fundamentals of Biochemistry: Life at the Molecular Level ,(1999)
Ivo Kabelka, Robert Vácha, Optimal conditions for opening of membrane pore by amphiphilic peptides. Journal of Chemical Physics. ,vol. 143, pp. 243115- 243115 ,(2015) , 10.1063/1.4933229
C. B. Park, K.-S. Yi, K. Matsuzaki, M. S. Kim, S. C. Kim, Structure–activity analysis of buforin II, a histone H2A-derived antimicrobial peptide: The proline hinge is responsible for the cell-penetrating ability of buforin II Proceedings of the National Academy of Sciences of the United States of America. ,vol. 97, pp. 8245- 8250 ,(2000) , 10.1073/PNAS.150518097
J. Lear, Z. Wasserman, W. DeGrado, Synthetic amphiphilic peptide models for protein ion channels Science. ,vol. 240, pp. 1177- 1181 ,(1988) , 10.1126/SCIENCE.2453923
W. F. Drew Bennett, Nicolas Sapay, D. Peter Tieleman, Atomistic Simulations of Pore Formation and Closure in Lipid Bilayers Biophysical Journal. ,vol. 106, pp. 210- 219 ,(2014) , 10.1016/J.BPJ.2013.11.4486
Sónia Troeira Henriques, Manuel Nuno Melo, Miguel A. R. B. Castanho, Cell-penetrating peptides and antimicrobial peptides: how different are they? Biochemical Journal. ,vol. 399, pp. 1- 7 ,(2006) , 10.1042/BJ20061100
Ming-Tao Lee, Fang-Yu Chen, Huey W. Huang, Energetics of pore formation induced by membrane active peptides Biochemistry. ,vol. 43, pp. 3590- 3599 ,(2004) , 10.1021/BI036153R
E. T. Kaiser, F. J. Kezdy, Secondary structures of proteins and peptides in amphiphilic environments. (A review). Proceedings of the National Academy of Sciences of the United States of America. ,vol. 80, pp. 1137- 1143 ,(1983) , 10.1073/PNAS.80.4.1137