Ciprofloxacin vs levofloxacin for prophylaxis during hematopoietic stem‐cell transplantation

作者: Vanessa Copeland , Milena McLaughlin , Steven Trifilio

DOI: 10.1111/CTR.13145

关键词: Multiple myelomaSurgeryAutologous hsctInternal medicineLevofloxacinMedicineRetrospective cohort studyHematopoietic stem cell transplantationIncidence (epidemiology)Cohort studyCiprofloxacin

摘要: The objective of the current retrospective study is to compare differences in rate breakthrough infections for ciprofloxacin versus levofloxacin prophylaxis an autologous HSCT patients treated multiple myeloma. This was a retrospective, cohort comparing hematopoietic stem-cell transplant (HSCT) recipients myeloma who received prophylaxis. A total 297 patients, 143 and 154 ciprofloxacin-treated were included. There significantly higher incidence bloodstream group (24/154) compared (10/143) p=0.03, primarily caused by statistically gram positive (ciprofloxacin (21/154) (8/143); p<0.01). Clinically relevant exist between fluoroquinolone agents used Levofloxacin more effective than reduce this study. This article protected copyright. All rights reserved.

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