Bacteremia Due to Viridans Group Streptococci with Diminished Susceptibility to Levofloxacin among Neutropenic Patients Receiving Levofloxacin Prophylaxis
作者： Raymund R. Razonable , Mark R. Litzow , Yasmin Khaliq , Kerryl E. Piper , Mark S. Rouse
DOI: 10.1086/340352
关键词: Gatifloxacin 、 Microbiology 、 Antibacterial agent 、 Gastroenterology 、 Internal medicine 、 Streptococcus 、 Transplantation 、 Levofloxacin 、 Neutropenia 、 Moxifloxacin 、 Bacteremia 、 Medicine
摘要: Despite the use of levofloxacin prophylaxis during neutropenic period after autologous peripheral blood stem cell transplantation, viridans group (VG) streptococcal bacteremia developed in 6 (16.2%) 37 patients who underwent transplantation between 1 January and 25 February 2001 at Mayo Clinic Rochester, Minnesota. All presented with fever mucositis a mean 4.5 days neutropenia, 3 septic shock. VG isolates from these exhibited distinct patterns on pulsed-field gel electrophoresis. had diminished susceptibility to levofloxacin, 5 gatifloxacin, 4 moxifloxacin. Quinolone resistance was associated mutations quinolone resistance-determining region GyrA (for isolate) ParC. The may select streptococci other quinolones enhanced activity against gram-positive organisms and, therefore, not be optimal for preventing patients.
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R. Novak, B. Henriques, E. Charpentier, S. Normark, E. Tuomanen, Emergence of vancomycin tolerance in Streptococcus pneumoniae Nature. ,vol. 399, pp. 590- 593 ,(1999) , 10.1038/21202
Daniel J Diekema, Ronald N Jones, Kenneth V.I Rolston, Antimicrobial activity of gatifloxacin compared to seven other compounds tested against Gram-positive organisms isolated at 10 cancer-treatment centers Diagnostic Microbiology and Infectious Disease. ,vol. 34, pp. 37- 43 ,(1999) , 10.1016/S0732-8893(99)00010-3
Pierre-Yves Bochud, Thierry Calandra, Patrick Francioli, Bacteremia due to viridans streptococci in neutropenic patients: A review The American Journal of Medicine. ,vol. 97, pp. 256- 264 ,(1994) , 10.1016/0002-9343(94)90009-4
P-Y Bochud, PH Eggiman, TH Calandra, G Van Melle, L Saghafi, P Francioli, Bacteremia Due to Viridans Streptococcus in Neutropenic Patients with Cancer: Clinical Spectrum and Risk Factors Clinical Infectious Diseases. ,vol. 18, pp. 25- 31 ,(1994) , 10.1093/CLINIDS/18.1.25
Eric J Bow, Lionel A Mandell, Thomas J Louie, Ronald Feld, Michael Palmer, Benny Zee, Joseph Pater, Quinolone-Based Antibacterial Chemoprophylaxis in Neutropenic Patients: Effect of Augmented Gram-Positive Activity on Infectious Morbidity Annals of Internal Medicine. ,vol. 125, pp. 183- 190 ,(1996) , 10.7326/0003-4819-125-3-199608010-00004
L. S. Elting, G. P. Bodey, B. H. Keefe, Septicemia and Shock Syndrome Due to Viridans Streptococci: A Case-Control Study of Predisposing Factors Clinical Infectious Diseases. ,vol. 14, pp. 1201- 1207 ,(1992) , 10.1093/CLINIDS/14.6.1201
Darrin J. Bast, Joyce C. S. de Azavedo, Tiffany Y. Tam, Laurie Kilburn, Carla Duncan, Lionel A. Mandell, Ross J. Davidson, Donald E. Low, Interspecies Recombination Contributes Minimally to Fluoroquinolone Resistance in Streptococcus pneumoniae Antimicrobial Agents and Chemotherapy. ,vol. 45, pp. 2631- 2634 ,(2001) , 10.1128/AAC.45.9.2631-2634.2001
David C. Classen, John P. Burke, Clyde D. Ford, Sherri Evershed, Mary R. Aloia, James K. Wilfahrt, John A. Elliott, Streptococcus mitis sepsis in bone marrow transplant patients receiving oral antimicrobial prophylaxis The American Journal of Medicine. ,vol. 89, pp. 441- 446 ,(1990) , 10.1016/0002-9343(90)90373-L
Robin Patel, Sharlene L Allen, Janice M Manahan, Alan J Wright, Ruud AF Krom, Russell H Wiesner, David H Persing, Franklin R Cockerill III, Rodney L Thompson, Natural history of vancomycin‐resistant enterococcal colonization in liver and kidney transplant recipients Liver Transplantation. ,vol. 7, pp. 27- 31 ,(2001) , 10.1053/JLTS.2001.20784
Christine C. Sanders, Mechanisms Responsible for Cross-Resistance and Dichotomous Resistance among the Quinolones Clinical Infectious Diseases. ,vol. 32, ,(2001) , 10.1086/319369