Increased plasma TGF‐β1 in patients with amyotrophic lateral sclerosis
作者： K. Houi , T. Kobayashi , S. Kato , S. Mochio , K. Inoue
DOI: 10.1034/J.1600-0404.2002.01301.X
关键词: Transforming growth factor 、 Amyotrophic lateral sclerosis 、 Blood plasma 、 In patient 、 Degenerative disease 、 Endocrinology 、 Internal medicine 、 Central nervous system disease 、 Medicine 、 Disease process 、 Plasma concentration
摘要: Objectives To investigate the levels of transforming growth factor-beta1 (TGF-beta1) in plasma patients with amyotrophic lateral sclerosis (ALS). Material and methods The TGF-beta1 concentrations were measured an enzyme-linked immunosorbent assay from 11 ALS 13 age matched healthy controls. Results mean concentration (2.15 +/- 0.80 ng/ml, SD) was significantly higher than controls (1.59 0.32 ng/ml) (P=0.031). There a significant positive correlation between duration illness (r=0.66, P=0.028). Conclusion Our findings provide evidence that increases illness. These results suggest is involved disease process ALS.
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