Age-related differences in volumes of subcortical nuclei, brain matter, and cerebrospinal fluid in healthy men as measured with magnetic resonance imaging

摘要: • Magnetic resonance imaging was used to determine the volumes of brain, subcortical gray matter nuclei, and ventricular sulcal cerebrospinal fluid in 27 healthy men. Subjects were divided into young ( 60 years, n= 17) groups. Volumes normalized as percent intracranial volume. Older subjects had significantly less brain mass larger peripheral than younger The caudate lenticular nuclei smaller older This significant difference remained when their expressed a ratio cerebral cross-sectional study demonstrates age-related atrophy concurrent dilation spaces subjects. Of regions affected, are more affected by aging is matter; this may account for some motor abnormalities aging.